Water insoluble polymer matrix for drug delivery

Details Water insoluble polymer matrix for drug delivery Water insoluble polymer matrix for drug delivery

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61F 9/00 (2006.01) A61K 47/30 (2006.01) A61P 27/00 (2006.01)

Patent

CA 2668814

Disclosed is a pharmaceutical composition comprising (a) a bioerodible water insoluble polymer matrix comprising a polyester polymer, wherein the polymer matrix has a melting point of less than 60°C and (b) an active agent dispersed within the polymer matrix, wherein the composition is formulated to controllably release the active agent for a pre-determined period of time to a target site. Also disclosed are methods of treating a disease or condition with the disclosed compositions.

L'invention concerne une composition pharmaceutique contenant (a) une matrice polymère insoluble de l'eau bioérodable contenant un polymère polyester, la matrice polymère présentant un point de fusion inférieur à 60°C, et (b) un principe actif dispersé dans la matrice polymère, la composition selon l'invention étant préparée de sorte à libérer le principe actif de façon régulée pendant une durée prédéterminée sur un site cible. L'invention concerne encore des méthodes de traitement d'une maladie ou d'une affection au moyen de ces compositions.

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