Water miscible macrolide solutions

Details Water miscible macrolide solutions Water miscible macrolide solutions

A - Human Necessities

61

K

A61K 31/7052 (2006.01) A61K 9/08 (2006.01) A61K 31/7042 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01) C07H 17/00 (2006.01)

Patent

CA 2336809

Water miscible pharmaceutical compositions containing up to about 40 % of a macrolide such as an azalide antibiotic are prepared by reaction of the macrolide with acid in a non-aqueous water miscible organic solvent system.

Cette invention concerne des compositions pharmaceutiques miscibles dans l'eau renfermant jusqu'à 40 % d'un macrolide tel qu'un antibiotique azalide. Ces préparations s'obtiennent en faisant réagir le macrolide avec un acide dans un système de solvant organique non aqueux miscible dans l'eau.

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