A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) C07H 1/00 (2006.01) C07H 17/08 (2006.01)
Patent
CA 2410886
The present invention provides two new classes of polyene macrolide amide derivatives useful for treating or preventing fungal infections. The new polyene macrolide amide derivatives exhibit antifungal activity and are more water-soluble than conventional polyene antibiotics, such as amphotericin B and amphotericin B methyl ester.
L'invention concerne deux nouvelles classes de dérivés amides de macrolides polyènes, utiles dans le traitement ou la prévention des infections fongiques. Les nouveaux dérivés amides de macrolides polyènes manifestent une activité antifongique et sont plus hydrosolubles que des antibiotiques traditionnels à base de polyène tels que les esters méthyliques d'amphotéricine B et d'amphotéricine A.
Baldwin Christopher J.
Chang Conway C.
Dang Binh T.
Loury David J.
Simon Reyna J.
Gowling Lafleur Henderson Llp
Micrologix Biotech Inc.
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