Water soluble derivatives of cephalexin and process for...

Details Water soluble derivatives of cephalexin and process for... Water soluble derivatives of cephalexin and process for...

C - Chemistry, Metallurgy

07

D

260/104.1

C07D 501/22 (2006.01) A61K 9/08 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01) C07D 501/04 (2006.01)

Patent

CA 1181741

ABSTRACT OF THE DISCLOSURE Water soluble derivatives of cephalexin, having general formula: Image wherein X represents the organic nitrogen containing cation of a basic aminoacid, combine the typical antibiotic action of cephalexin with the water solubility and form essentially neutral, aqueous solutions. The process for the preparation of the above derivatives comprises a first step in which the methylol derivative of cephalexin is prepared and a second step in which the treatment with a suitable base is carried out.

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