C - Chemistry – Metallurgy – 09 – B
Patent
C - Chemistry, Metallurgy
09
B
C09B 47/04 (2006.01) C09B 47/00 (2006.01) C09B 47/06 (2006.01) C09B 47/08 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2350608
The present invention thus relates to marker components, fluorescent probes, oligonucleotides, hybridization assays, and immunoassays using such products and methods for making such products. According to the present invention, detectably labeled marker components are provided that comprise a fluorophore moiety coupled to two or more small solubilizing axial ligands, [define] which preferably reduce or remove the problems of solvent sensitivity and non- specific binding.
La présente invention concerne des composants marqueurs, des sondes fluorescentes, des oligonucléotides, des dosages d'hybridation, et des immunodosages utilisant de tels produits et des procédés de fabrication de tels produits. Cette invention concerne des composants marqueurs, marqués de manière détectable, qui comprennent une entité fluorophore couplée à un ou deux petits ligands axiaux solubilisants, qui permettent préférablement de réduire ou d'éliminer les problèmes de sensibilité au solvant et de liaisons non spécifiques.
Dandliker Walter B.
Hsu Mao Lin
Hyperion Inc.
Smart & Biggar
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