C - Chemistry – Metallurgy – 09 – K
Patent
C - Chemistry, Metallurgy
09
K
358/11, 31/153,
C09K 11/06 (2006.01) G01T 1/204 (2006.01) G01T 1/29 (2006.01) G03B 42/02 (2006.01)
Patent
CA 1193089
ABSTRACT OF THE DISCLOSURE Water soluble fluors useful in enhancing images obtained in autoradiography have the general formula: Image F is a moiety which acts as a fluor, e.g., a dehydro derivative of a compound which is a fluor; preferred examples include 4-(2,5-diphenyloxazolyl), l-naphthylmethyl, 2-naphthyl, and 4-[5-(2-phenyloxazolyl)]phenyl. S is a surfactant moiety which makes the molecule hydrophilic, e.g., (dehydro derivatives of surfactants; preferred examples include polyethylene glycol derivatives, sulfonic acids or salts thereof, aryl sulfonates, amines and quaternary ammonium compounds. B is a hinding moiety which chemically binds the fluor moiety F with the surfactant S, and may be a chemical bond, or a disubstituted moiety such as an alkylene, e.g., methylene group. The variables x, y and z are integers which can generally vary from 1 to 10. A number of such compounds are disclosed, as well as methods of using such compounds, as well as compositions and products for fluorographic analysis in connection with chromatography, electrophoresis etc.
414674
Feierberg Susan
Lee Duk H.
O'brien Robert E.
Marcoux & Sher Swabey Mitchell Houle
Nen Life Science Products Inc.
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