C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2345376
The present invention provides a water-soluble luminescent quantum dot, a biomolecular conjugate thereof and a composition comprising such a quantum dot or conjugate. Additionally, the present invention provides a method of obtaining a luminescent quantum dot, a method of making a biomolecular con-jugate thereof, and methods of using a biomolecular conjugate for ultrasensi-tive nonisotopic detection in vitro and in vivo.
L'invention concerne un point quantique luminescent soluble dans l'eau, son conjugué biomoléculaire et une composition comprenant ce point quantique ou ce conjugué. De plus, l'invention concerne un procédé d'obtention d'un point quantique luminescent, un procédé de préparation de son conjugué biomoléculaire et des procédés d'utilisation d'un conjugué biomoléculaire pour une détection nonisotopique ultrasensible in vitro et in vivo.
Chan Warren C.w.
Emory Steven R.
Nie Shuming
Advanced Research And Technology Institute Inc.
Indiana University Research And Technology Corporation
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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