Water soluble non-immunogenic polyamide cross-linking agents

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 69/00 (2006.01) A61K 47/34 (2006.01) A61K 47/48 (2006.01) C08F 8/30 (2006.01)

Patent

CA 2156924

The present invention relates to water-soluble nonimmunogenic polyamide cross- linking agents and their use to cross-link, polymerize, decorate, and conjugate proteins, polynucleotides and other biological substrates to form substantially nonimmunogenic water-soluble products. The present invention also relates to proteins, polynucleotides and other biological substrates which are cross-linked, conjugated, polymerized or decorated with water- soluble polyamides to form substantially nonimmunogenic products.

La présente invention concerne des agents de réticulation à base de polyamides non immunogène hydrosoluble et leur emploi pour réticuler, polymériser, décorer et conjuguer des protéines, des polynucléotides et autres substrats biologiques afin de constituer des produits hydrosolubles non immunogènes. La présente invention concerne des protéines, des polynucléotides et autres substrats biologiques qu'il est possible de réticuler, conjuguer, polymériser ou décorer au moyen de polyamides hydrosolubles, pour constituer des produits essentiellement non immunogènes.

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