Water soluble polyvinyl lactam-drug complexes

Details Water soluble polyvinyl lactam-drug complexes Water soluble polyvinyl lactam-drug complexes

A - Human Necessities

61

K

167/166, 167/213

A61K 31/38 (2006.01) A61K 9/14 (2006.01) A61K 31/40 (2006.01) A61K 47/48 (2006.01) C07D 207/12 (2006.01) C08F 8/00 (2006.01)

Patent

CA 1281651

WATER SOLUBLE POLYVINYL LACTAM-DRUG COMPLEXES ABSTRACT The invention relates to water soluble complexes of normally water insoluble drugs such as chlorothiazide, aminobenzoic acid, furosemide and mixtures thereof wherein the complexing agent is a polyvinyl lactam such as polyvinylpyrrolidone, polyvinylpyrrolidone-halogen complex or mixtures thereof. The invention also relates to the preparation of these complexes which involves dissolving the reactive components in an aqueous inert solvent combining the complexing agent and drug in a weight ratio of from about 1:1 to about 10:1 with agitation for a period of at least 5 minutes at a temperature above 3°C. and below the boiling point of the aqueous solvent solution under a pressure up to about 50 psig.

534288

Affiliated with

Also associated with

Rating

Water soluble polyvinyl lactam-drug complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Water soluble polyvinyl lactam-drug complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Water soluble polyvinyl lactam-drug complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1243020