Water soluble rapamycin esters

Details Water soluble rapamycin esters Water soluble rapamycin esters

C - Chemistry, Metallurgy

07

D

C07D 498/18 (2006.01) A61K 31/4353 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2421485

This invention provide pegylated hydroxyesters of rapamycin which are useful in inducing immunosuppression and in the treatment of transplantation rejection, autoimmune diseases, solid tumors, fungal infections, and vascular disease.

L'invention concerne des hydroxyesters pegylés de la rapamycine permettant d'activer l'immunosuppression et utilisés dans le traitement d'un rejet lors d'une transplantation, de maladies auto-immunes, de tumeurs solides, d'infections fongiques, et de maladies vasculaires.

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