A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/12 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 31/4965 (2006.01) A61K 31/727 (2006.01) A61K 38/08 (2006.01) A61K 38/13 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61K 38/28 (2006.01) A61K 39/395 (2006.01) A61M 11/00 (2006.01)
Patent
CA 2637036
The invention relates to an aerosol formulation system comprising a primary package system and an aerosol formulation therein wherein the aerosol formulation comprises insulin, a propellant and an amount of water sufficient to reach equilibrium quantities based on the moisture sorption rate diffusing across the primary package system in which the formulation is contained. In addition, the invention relates to a process for preparing the aerosol formulation systems as described herein.
La présente invention concerne un système de formulation d'aérosol qui comprend un système d'emballage primaire et une formulation d'aérosol contenue dans ce dernier. La formulation d'aérosol renferme de l'insuline, un agent propulseur et une quantité d'eau suffisante pour atteindre des quantités d'équilibre reposant sur la vitesse de sorption de l'humidité se diffusant dans le système d'emballage primaire contenant la formulation. De plus, l'invention porte sur un procédé de préparation des systèmes de formulation d'aérosol, tels que susmentionnés.
Adjei Akwete
Cutie Anthony J.
Zhu Yaping
Abbott Respiratory Llc
Kos Life Sciences Inc.
Torys Llp
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