A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/179
A61K 31/13 (2006.01) A61K 31/185 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/405 (2006.01) A61K 31/455 (2006.01) A61K 31/54 (2006.01) A61K 31/60 (2006.01) A61K 47/18 (2006.01) C07C 57/30 (2006.01) C07C 59/64 (2006.01) C07C 59/68 (2006.01) C07C 59/84 (2006.01)
Patent
CA 1177398
Abstract of the Disclosure The invention relates to water-soluble derivatives of non-steroidal anti-inflammatory drugs and also to therapeutic compositions containing these derivatives. The compounds used in the therapeutic compositions have an aromatic nucleus, one or more hydrophobic side chains and an acid group and a hydrophylic component selected from the group comprising of tris(hydroxy- methyl)aminomethane; [bis(2-hydroxyethyl)-amino]-tris(hydroxymethyl)methane, 1,3-bis[tris(hydroxymethyl)-methylaminopropane, 3-[tris(hydroxymethyl)- methyl]-aminopropanesulfonic acid, 2-[tris(hydroxymethyl)methyl]-amino- ethanesulfonic acid and N-[tris(hydroxymethyl)methyl]-glycine or a mixture thereof. The compounds are useful in the treatment of degenerative joint diseases, arthritis, inflammatory locomotor diseases, gout, spondylitis and related diseases.
361122
Fetherstonhaugh & Co.
Kahan Ilona Nee Laszlo
LandOfFree
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