C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/40 (2006.01) A61K 31/7088 (2006.01) A61K 35/76 (2006.01) A61K 39/12 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 31/14 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) C12N 1/20 (2006.01) C12N 7/00 (2006.01) C12N 7/04 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2456873
The present invention relates to the development of viral vectors expressing different immunogens from the West Nile Encephalitis Virus (WNV) or the Dengue virus which are able to induce protective humoral and cellular immune responses against WNV or Dengue virus infections. Mare specifically, the present invention relates to three (3) antigens from WNV (the secreted envelope glycoprotein (E), the heterodimer glycoproteins (pre-M-E) and the NS1 protein) and from Dengue virus (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre- m-e) and the ns1 protein) and their use in vaccinal, therapeutic and diagnostic applications.
Combredet Chantal
Despres Philippe
Frenkiel Marie Pascale
Tangy Frederic
Centre National de La Recherche Scientifique (c.n.r.s.)
Institut Pasteur
Robic
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