C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/02 (2006.01) A61K 31/70 (2006.01) A61K 31/7056 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 25/06 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) C07H 17/00 (2006.01)
Patent
CA 2538905
Novel isolated and purified withanamides and withanolides are described. In particular, compounds from Withania somnifera fruit are the preferred source of the withanamides and withanolides, although they can be from other plant sources. In addition to their use as powerful antioxidants, the withanamides and withanolides can be useful for the treatment of depression, Alzheimer's Disease, obesity and migraine headaches.
La présente invention concerne de nouvelles withanamides et de nouvelles withanolides isolées et purifiées. Cette invention concerne en particulier des composés issus du fruit<i>Withania somnifera</i> qui est la source préférée des withanamides et des withanolides, bien qu'elles puissent provenir d'autres sources végétales. Outre leur utilisation sous forme d'antioxydants puissants, les withanamides et les withanolides conviennent pour le traitement de la dépression, de la maladie d'Alzheimer, de l'obésité et des maux de tête de migraine.
Jayaprakasam Bolleddula
Nair Muraleedharan G.
Macrae & Co.
Michigan State University
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