Wnt-1 inhibitory factor-1 (wif-1) molecules and uses thereof

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/08 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 19/02 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2511245

The present invention provides Wnt-1 Inhibitory Factor-1 (WIF-1) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing WIF-1 polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with WIF-1 polypeptides.

L'invention concerne des polypeptides du facteur-1 inhibiteur de Wnt-1 (WIF-1) et des molécules d'acides nucléiques les codant. L'invention concerne également des agents de liaison sélectifs, des vecteurs, des cellules hôtes, ainsi que des procédés de production de ces polypeptides. Elle concerne en outre des compositions pharmaceutiques et des procédés de diagnostic, de traitement et d'amélioration, et/ou de prévention de maladies, de troubles et d'états associés aux polypeptides WIF-1.

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