C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/10 (2006.01) A61K 31/403 (2006.01) A61K 31/4709 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 3/10 (2006.01) A61P 19/10 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C07D 209/76 (2006.01) C07D 401/12 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2726164
The present invention generally relates to protein signalling. In particular, compounds that inhibit the Wnt protein signalling pathway are disclosed. Such compounds may be used in the treatment of Wnt protein signalling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.
De façon générale, la présente invention concerne la signalisation de la protéine Wnt et, en particulier, des composés qui inhibent la voie de signalisation de cette protéine. De tels composés peuvent s'utiliser pour le traitement de maladies et d'états pathologiques en rapport avec la signalisation de la protéine Wnt tels que le cancer, les maladies dégénératives, le diabète de type II et l'ostéoporose.
Chen Baozhi
Chen Chuo
Dodge Michael
Lum Lawrence
Roth Mike
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Board Of Regents Of The University Of Texas System
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