Wnt-regulated cytokine-like polypeptide and nucleic acids...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C07K 14/52 (2006.01) C07K 14/705 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 1/21 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2391380

The present invention provides novel polypeptides, termed FCTRX polypeptides, as well as polynucleotides encoding FCTRX polypeptides and antibodies that immunospecifically bind to an FCTRX or a derivative, variant, mutant, or fragment of an FCTRX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FCTRX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.

Cette invention a trait à de nouveaux polypeptides, dénommés polypeptides FCTRX, ainsi qu'à des polynucléotides codant ceux-ci et à des anticorps se fixant de manière immunospécifique à un polypeptide FCTRX ou à un dérivé, un variant, un mutant ou encore à un fragment dudit polypeptide, polynucléotide ou anticorps. L'invention qui concerne, de surcroît, des méthodes de détection et de traitement d'un large éventail d'états pathologiques, lesquelles méthodes utilisent les polypeptides FCTRX ainsi que les polynucléotides et anticorps susmentionnés, porte également sur d'autres emplois de ceux-ci.

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