Wnt1 as a renal damage biomarker

Details Wnt1 as a renal damage biomarker Wnt1 as a renal damage biomarker

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2733964

The present invention comprises the use of WNT1 as a biomarker in the monitoring, prognosis and /or in the diagnosis of chronic nephropathies. It provides in vitro prognostic and diagnostic methods and kits for its implementation. The present invention also comprises the use of WNT1 in screening active ingredients for the manufacture of a drug for therapies for chronic nephropathies and a method for conducting said screening.

La présente invention concerne lutilisation de WNT1 en tant que biomarqueur dans la surveillance, le pronostic et/ou le diagnostic de néphropathies chroniques. La présente invention concerne des procédés et des trousses de pronostic et de diagnostic in vitro pour sa mise en uvre. La présente invention concerne en outre lutilisation de WNT1 dans le criblage de principes actifs pour la fabrication dun médicament pour des thérapies pour des néphropathies chroniques et un procédé pour conduire ledit criblage.

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