Wortmannin conjugates and uses thereof

Details Wortmannin conjugates and uses thereof Wortmannin conjugates and uses thereof

C - Chemistry, Metallurgy

07

J

C07J 71/00 (2006.01) A61K 9/00 (2006.01) A61K 31/585 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01) A61P 31/10 (2006.01) A61P 35/00 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2620855

The invention features conjugates of wortmannin, and wortmannin derivatives, and their use as inhibitors of PI3 -kinase activity in treating cancer, inflammatory diseases, and C. albicans infections.

Cette invention concerne des conjugués de la wortmannine et des dérivés de la wortmannine, ainsi que leur utilisation comme inhibiteurs de l'activité de la PI3-kinase dans le traitement du cancer, de maladies inflammatoires et d'infections à C. Albicans.

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