Wortmannin-rapalog conjugate and uses thereof

Details Wortmannin-rapalog conjugate and uses thereof Wortmannin-rapalog conjugate and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 519/00 (2006.01) A61K 31/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2680683

An anti-neoplastic wortmannin conjugate is described formed by a linking a rapalog and wortmannin. Such a linkage is removable following administration to a subject. Use of such a conjugate in an antineoplastic regimen is described.

L'invention porte sur un conjugué de wortmannine antinéoplasique, qui est formé par une liaison d'un rapalog et de la wortmannine. Une telle liaison est apte à être retirée après l'administration à un sujet. L'invention porte sur une utilisation d'un tel conjugué dans un régime antinéoplasique.

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