Wound dressings comprising a protein polymer and a...

A - Human Necessities – 61 – L

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A61L 15/60 (2006.01) A61L 15/32 (2006.01) A61L 17/06 (2006.01) A61L 27/22 (2006.01)

Patent

CA 2556426

There is described a method of forming a wound dressing. The method comprises forming a protein polymer by reacting a protein with a polyfunctional spacer, or an activated derivative thereof. The polyfunctional spacer is preferably a polycarboxylic acid, especially a dicarboxylic acid, and protein polymers prepared using such spacers are suitable for a wide range of therapeutic applications, including use as wound dressings, for the delivery of therapeutically active agents to the body and as bioadhesives and sealants.

L'invention concerne un procédé de formation d'un pansement. Le procédé comporte les étapes consistant à : former un polymère protéique par la mise en réaction d'une protéine avec un espaceur polyfonctionnel ou un dérivé activé de celui-ci. L'espaceur polyfonctionnel est de préférence un acide polycarboxylique, notamment un acide dicarboxylique, et les polymères protéiques préparés à l'aide de ces espaceurs conviennent pour un large éventail d'applications thérapeutiques, y compris comme pansements, pour l'apport d'agents thérapeutiquement actifs et comme bioadhésifs et produits de scellement.

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