Wound dressings with protease-lowering activity

Details Wound dressings with protease-lowering activity Wound dressings with protease-lowering activity

A - Human Necessities

61

L

A61L 15/28 (2006.01) A61L 15/44 (2006.01)

Patent

CA 2401582

The invention provides wound dressings and methods of their use, especially for the treatment of chronic, non-healing wounds. The wound dressings are composed of a support matrix, such as cotton cellulose, and an active agent associated with the support matrix. The active agent may be a protease inhibitor or a protease sequestrant, in particular an inhibitor or sequestrant of a neutrophil-derived cationic protease such as elastase.

L'invention concerne des pansements et des procédés d'utilisation de ceux-ci, notamment dans le traitement de plaies chroniques, ou qui ne cicatrisent pas. Ces pansements sont constitués d'une matrice support, telle qu'une cellulose de coton, et d'un principe actif associé cette matrice. Le principe actif peut être un inhibiteur de protéase ou un séquestrant de protéase, en particulier un inhibiteur ou un séquestrant de protéase cationique issue de neutrophiles, telle que l'élastase.

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