A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/36 (2006.01) A61K 38/36 (2006.01) A61L 27/60 (2006.01) A61P 17/02 (2006.01)
Patent
CA 2556098
The present invention relates to compositions and methods for tissue regeneration, particularly for treating skin lesions such as wounds. In one aspect, the invention provides a wound healing composition comprising living cells such as fibroblasts within a support matrix such as fibrin, in which the cells have a wound healing phenotype, and in which the composition is single~ layered and has been incubated for up to about 8 days to allow development of the wound healing phenotype. The compositions and methods of the invention are useful especially for assisting the process of wound healing, particularly chronic open lesions that are slow to heal or resistant to healing.
La présente invention concerne des compositions et des méthodes de régénération de tissus, destinées notamment au traitement de lésions cutanées telles que des plaies. Dans un aspect, l'invention concerne une composition de cicatrisation contenant des cellules vivantes telles que des fibroblastes à l'intérieur d'une matrice de support telle que la fibrine, dans laquelle les cellules ont un phénotype de cicatrisation et dans laquelle la composition se présente sous la forme d'une monocouche et a été incubée pendant une durée allant jusqu'à 8 jours pour permettre le développement du phénotype de cicatrisation. Les compositions et les méthodes de l'invention sont utiles notamment pour aider le processus de cicatrisation, en particulier les lésions chroniques ouvertes qui sont lentes à cicatriser ou résistantes à la cicatrisation.
Batten Margaret
Johnson Penelope Ann
Kemp Paul
Mcwhan Michael
Shering Andrew
Bcf Llp
Dfb Technology Holdings Llc
Intercytex Limited
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