Wound healing compositions and treatments

Details Wound healing compositions and treatments Wound healing compositions and treatments

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2711635

Methods and compositions comprising an anti-ostepontin agent and/or a PDGF receptor blocker or antagonist, alone or in combination with one or more anti-connexin agents, for example, one or more anti-connexin polynucleotides and/or one or more anti-connexin peptides or peptidomimetics, are provided for the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.

L'invention concerne des procédés et des compositions qui comprennent un agent anti-ostépontine et/ou un antagoniste ou un bloqueur du récepteur PDGF, seul ou en combinaison avec un ou plusieurs agents anti-connexine, par exemple un ou plusieurs polynucléotides anti-connexine et/ou un ou plusieurs peptides ou peptidomimétiques anti-connexine, destinés à favoriser et/ou améliorer la guérison de blessures et/ou la réparation tissulaire, ainsi que pour des indications anti-cicatrisation, anti-inflammation, anti-fibrose et anti-adhésion.

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