Wound healing method and kits

Details Wound healing method and kits Wound healing method and kits

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) A01N 63/00 (2006.01) A61K 48/00 (2006.01) A61N 1/30 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2511315

Electroporation is used to enhance the wound-healing benefit provided by transfection of nucleic acids that encode cellular growth factors. Wounds which are amenable to the method include inter alia cutaneous lesions, muscular lesions, osseus lesions, burn wounds, and gastrointestinal anastamoses. Kits comprise electrodes and nucleic acids encoding cellular growth factors.

L'invention concerne l'utilisation de l'électroporation pour améliorer le bénéfice de la subérification obtenue par la transfection d'acides nucléiques qui sont codants pour les facteurs de croissance cellulaire. Les blessures qui relèvent de ce procédé sont notamment des lésions cutanées, des lésions musculaires, des lésions osseuses, des brûlures et des anastomoses gastro-intestinales. Les trousses comprennent des électrodes et des acides nucléiques codants pour les facteurs de croissance cellulaire.

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