A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/711 (2006.01) C12N 15/11 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2471967
The present invention provides methods for inhibiting the growth of breast cancer cells and methods for treating breast cancers expressing Wilms' Tumor 1 (WT1) gene product using a WT1 antisense oligonucleotide. It further provides methods of predicting breast cancer progression and methods for the screening of candidate substances for activity against breast cancer.
La présente invention concerne des méthodes pouvant inhiber la croissance de cellules cancéreuses du sein, et des méthodes de traitement de cancers du sein exprimant le produit génique de la tumeur de Wilms 1 (WT1) au moyen d'un oligonucléotide antisens. L'invention concerne en outre des méthodes permettant de prédire l'évolution du cancer du sein, et des méthodes de criblage de substances candidates agissant contre le cancer du sein.
Lopez-Berestein Gabriel
Tari Ana Maria
Zapata-Benavides Pablo
Board Of Regents The University Of Texas System
Goudreau Gage Dubuc
LandOfFree
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