C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) A61K 35/12 (2006.01) A61K 35/76 (2006.01) A61K 38/04 (2006.01) A61P 35/00 (2006.01) C07K 7/04 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 16/30 (2006.01) C07K 16/32 (2006.01) C07K 19/00 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/00 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2544214
It is intended to provide a WT1-origin HLA-DRB1*0405-binding antigen peptide; a polynucleotide encoding this peptide; a helper T cell-inducing agent containing the peptide or the polynucleotide; and so on. A peptide which is a partial peptide comprising from 10 to 25 consecutive amino acids in the human WT1 amino acid sequence represented by SEQ ID NO:1 and binding to HLA- DRB1*0405 to induce helper T cells; a polynucleotide encoding this peptide; a helper T cell-inducing agent containing the peptide or the polynucleotide; and so on.
L'invention concerne un peptide antigène se liant à HLA-DRB1*0405 d'origine WT1. L'invention concerne un polynucléotide codant ce peptide, un agent d'induction de cellule T assistante contenant le peptide ou le polynucléotide de l'invention, etc. L'invention concerne un peptide qui est un peptide partiel comprenant de 10 à 25 acides aminés consécutifs dans la séquence d'acides aminés WT1 humaine représentée par SEQ ID NO:1, et se liant à HLA-DRB1*0405 pour induire des cellules T assistantes. L'invention concerne un polynucléotide codant ce peptide, un agent d'induction de cellule T assistante contenant ce peptide ou ce polynucléotide, etc.
International Institute Of Cancer Immunology Inc.
Kirby Eades Gale Baker
LandOfFree
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