X-ray contrast material for the gastrointestinal tract

Details X-ray contrast material for the gastrointestinal tract X-ray contrast material for the gastrointestinal tract

C - Chemistry, Metallurgy

07

C

167/36, 260/510.

C07C 233/53 (2006.01) A61K 49/04 (2006.01) C07C 233/54 (2006.01) C07C 233/55 (2006.01) C07C 237/46 (2006.01) C08F 226/06 (2006.01)

Patent

CA 2031739

34447/SOVA 3-1 X-RAY CONTRAST MATERIALS FOR THE GASTROINTESTINAL TRACT ABSTRACT OF THE DISCLOSURE Hydroxyalkyl amino-substituted triiodoben- zoates are provided, where the remaining position is substituted by amino or carboxy. The compounds have low solubility in the gastrointestinal tract, but are resorbable from extravisceral body cavities. They can be readily formulated and used as contract media for the plain radiography of the GI tract. Also, addition polymers comprised of triiodo compounds bonded through an amino nitrogen to a non-oxo- carbonyl group of an addition polymerizable monomer are provided. The polymers are highly water soluble physiologically acceptable, and not resorbable from the GI tract, but from the extravisceral body cavities. The polymers find use for computer tomography of the GI tract. 20219945 35. 081790

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