X-ray contrast media

C - Chemistry – Metallurgy – 07 – C

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Details

260/473.5, 260/5

C07C 233/12 (2006.01)

Patent

CA 1105481

ABSTRACT OF THE DISCLOSURE This invention relates to compounds of the formula: Image (I) in which: R1 represents a hydrogen atom or a C1-4alkyl radical or a C1-4 hydroxyalkyl radical, R2 represents a C1-4 alkyl radical or a C1-4 hydroxyalkyl radical, A represents a group of the formula: Image in which : R3 represents a hydrogen atom, a group of the formula Image in which R5 and R6 represent each a hydrogen atom or a C1-4 alkyl radical or a C1-4 hydroxyalkyl radical, or a group of the formula Image in which R7 represents a C1-4 alkyl radical or a C1-4 hydroxyalkyl radical and R8 represents a hydrogen atom, a C1-4 alkyl radical or a C1-4 hydroxyalkyl radical, n is o or 1 and n is an integer from 1 to 5 inclusive, R4 represents a hydrogen atom or a C1-4 alkyl radical or a C 1-4hydroxyalkyl radical, their methyl and ethyl esters and their salts with pharmaceutically acceptable bases. Said compounds are useful as X-ray contrast media.

275511

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