X-ray emitting interstitial implants

Details X-ray emitting interstitial implants X-ray emitting interstitial implants

A - Human Necessities

61

K

A61K 51/00 (2006.01) A61M 36/12 (2006.01) A61N 5/10 (2006.01)

Patent

CA 2199945

Safe, isotopically pure Pd-103-containing seeds (10) of high apparent activity are formed by bombarding an Rh target in a cyclotron with high energy particles to obtain Rh containing carrier-free Pd-103, separating therefrom the carrier-free Pd-103, adding a small amount of Pd to the carrier-free Pd- 103, electroplating said Pd-103/Pd admixture to a pellet(s) (14) of electroconductive material and encapsulating the pellet(s) (14) within a bi- compatible container or shell (22).

L'invention porte sur la préparation de grains (10) à haute radioactivité apparente, contenant du palladium-103, non-toxique et isotopiquement pur. Le procédé comporte plusieurs opérations: bombardement d'une cible de rhodium dans un cyclotron avec des particules de haute énergie en vue d'obtenir du palladium-103 sans particule chargée contenant du rhodium; séparation du palladium-103 du rhodium; ajout d'une petite quantité de palladium au palladium-103; électrodéposition de ce produit d'addition Pd-103/Pd sur une ou plusieurs granules (14) de matériau électro-conducteur et encapsulation de celle(s)-ci dans un récipient ou une enveloppe biocompatible (22).

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