C - Chemistry – Metallurgy – 09 – B
Patent
C - Chemistry, Metallurgy
09
B
C09B 11/24 (2006.01) C07H 21/00 (2006.01) C09B 11/02 (2006.01) C12Q 1/34 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/533 (2006.01) G01N 33/542 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2335359
The quenching compounds of the invention are nitrogen-substituted xanthenes that are substituted by one or more aromatic or heteroaromatic quenching moieties. The quenching compounds of the invention exhibit little or no observable fluorescence and efficiently quench a broad spectrum of luminescent compounds. The chemically reactive quenching compounds possess utility for labeling a wide variety of substances, including biomolecules. These labeled substances are highly useful for a variety of energy-transfer assays and applications.
Les composés d'extinction de l'invention sont des xanthènes substitués en azote qui sont substitués par un ou plusieurs groupes fonctionnels aromatiques ou hétéro-aromatiques. Les composés d'extinction de l'invention manifestent peu ou pas de fluorescence et éteignent efficacement un large spectre de composés luminescents. Les composés d'extinction chimiquement réactifs peuvent s'utiliser pour étiqueter une large gamme de substances, y compris les biomolécules. Ces substances étiquetées sont très utiles dans divers dosages et applications liés au transfert de l'énergie.
Haugland Richard P.
Singer Victoria L.
Yue Stephen T.
Mbm Intellectual Property Law Llp
Molecular Probes Inc.
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