Xanthine compound, method for preparing thereof, and a...

Details Xanthine compound, method for preparing thereof, and a... Xanthine compound, method for preparing thereof, and a...

C - Chemistry, Metallurgy

07

D

167/220, 260/242

C07D 473/04 (2006.01) A61K 31/52 (2006.01)

Patent

CA 2030112

ABSTRACT: A novel xanthine compound having bronchodilating and brain function improving activity represented by the following formula (I) and (II): Image ( I ) Image ( II ) wherein R1 represents a hydrogen atom, 4-methoxybenzyl group, a straight- or branched-chain alkyl group having 1 to 6 carbon atoms, or a cycloalkyl group having 3 to 6 carbon atoms; R2 represents a hydrogen atom, a straight- or branched-chain alkyl group having 1 to 6 carbon atoms, or a cycloalkyl group having 3 to 6 carbon atoms; n represents an integer of from 1 to 4; and A represents -COCH3 or - C(OR3)(OR4)CH3 in which R3 and R4 independently represents an alkyl group having 1 to 3 carbon atoms or R3 together with R4 represents a polymethylene group having 2 to 4 carbon atoms is disclosed. Also 6 0 disclosed are a pharmacologically acceptable salt of the same, method for preparing the same, and a pharmaceutical composition for the treatment of respiratory tract disease or brain disfunction comprising the effective amount of same. 61

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