Xanthine compounds and method of treating bronchospastic and...

C - Chemistry – Metallurgy – 07 – D

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260/242.4

C07D 473/06 (2006.01) C07D 239/545 (2006.01)

Patent

CA 1077932

ABSTRACT OF THE DISCLOSURE: Bronchial asthma and other bronchospastic and allergic diseases are treated by administering an effective amount of a substituted xanthine compound having the formula: Image wherein: R1 = C1-C2 alkyl, R3 = -CH2-(C3-C4) alkyl, -CH2-(C3-C4 cycloalkyl) R7 = H, COOR R8 = H, C1-C4 alkyl R = C1-C4 alkyl, 2-halo-C3-C3 alkyl, or phenyl Provided: R7 AND R8 are not H simultaneously. The bronchodilator and antiallergy agents may be administered the form of tablets, capsules, aerosols, solutions, suspensions or suppositories.

274520

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