Xanthine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 473/06 (2006.01)

Patent

CA 2094270

The present invention relates to novel xanthine derivatives of the formula (I) which are selectively antagonistic to an adenosine A2 receptor, and pharmaceutically acceptable salts thereof. Formula (I): Image (?) In the formula, R1 and R are the same or different and each represents a hydrogen atom, a propyl group, a butyl group or an allyl group; R3 represents a hydrogen atom or a lower alkyl group; Y1 and Y are the same or different and each represents a hydrogen atom or a methyl group; and Z represents a substituted or unsubstituted phenyl group, a pyridyl group, an imidazolyl group, a furyl group or a thienyl group.

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