Xanthine derivatives as selective hm74a agonists

Details Xanthine derivatives as selective hm74a agonists Xanthine derivatives as selective hm74a agonists

C - Chemistry, Metallurgy

07

D

C07D 473/06 (2006.01) A61K 31/495 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) C07D 473/04 (2006.01)

Patent

CA 2626723

The present invention relates to compounds1 of formula (I) which are xanthine derivatives, processes for the manufacture of said derivatives, pharmaceutical formulations containing these, compounds and the use of the compounds in therapy, for example, in the treatment of diseases where under-activation of the HM74A receptor contributes to the disease or where activation of the receptor will be beneficial.

La présente invention concerne des composés de formule (I) qui sont des dérivés de la xanthine, des procédés pour la fabrication desdits dérivés, des formulations pharmaceutiques les contenant, des composés et l~utilisation des composés pour une thérapie, par exemple, pour traiter des maladies dans lesquelles la sous activation du récepteur HM74A contribue à la maladie ou lorsque l~activation du récepteur peut être bénéfique.

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