Xanthone derivatives and process for producing the same

C - Chemistry – Metallurgy – 07 – D

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260/356.1, 260/3

C07D 311/86 (2006.01) C07D 493/04 (2006.01)

Patent

CA 1234126

XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME Abstract of the Disclosure: Xanthone derivatives of the formula (I): Image (I) (wherein W, X, Y and Z which may be the same or different represent a hydrogen atom, a halogen atom or a lower alkyl group having 1 to 4 carbon atoms; A is a hydrogen atom or may bind to X or Y to form a cyclic methylene chain; B is a hydroxymethyl group, a lower alkoxycarbonyl group having 1 to 4 carbon atoms, or a carboxyl group, provided that W is neither a hydrogen atom nor a 7-position methyl group when X, Y and Z are each a hydrogen atom, and A is a hydrogen atom and B is a carboxyl group or a lower alkoxycarbonyl group), as well as intoxic salts thereof when B is a carboxyl group, and a process for preparing the same are disclosed. The compounds of formula (I) in accordance with the present invention are useful as diuretics having uricosuric activity and can be used in the treatment of edema or hypertension.

491080

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