Xenobiotic animal model of h. pylori infection

A - Human Necessities – 01 – K

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A01K 67/027 (2006.01)

Patent

CA 2283401

An animal model for experimental infection with Helicobacter pylori which displays the acute symptoms of Helicobacter pylori infection. The model can be prepared by injecting an animal, such as a xenobiotic dog, with a dose of bacteria previously adapted to the mouse. The invention also relates to the use of the animal model for the development of vaccines, chemotherapeutics and diagnostics.

L'invention concerne un modèle animal qui peut être infecté expérimentalement par Helicobacter pylori et qui présente les symptômes aigus d'une infection à Helicobacter pylori. On prépare ledit modèle en injectant à un animal, tel qu'un chien xénobiotique, une dose de bactéries antérieurement adaptées à la souris. L'invention concerne également l'utilisation d'un modèle animal pour le développement de vaccins, de médicaments chimiques et de méthodes diagnostiques.

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