Xylose reductase mutants and uses thereof

Details Xylose reductase mutants and uses thereof Xylose reductase mutants and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 9/04 (2006.01) C12N 15/53 (2006.01) C12P 7/18 (2006.01)

Patent

CA 2692963

Engineered mutant xylose reductases demonstrate higher preference to xylose than arabinose. Amino acid mutations were engineered in to native xylose reductase from Neurospora crassa. Mutant xylose reductases are useful in the production of xylitol and ethanol.

L'invention concerne des xylose réductases mutantes modifiées démontrant une préférence au xylose plus élevée qu'à l'arabinose. Des mutations d'acides aminés ont été mises au point dans de la xylose réductase native provenant de Neurospora crassa. Les réductases de xylose mutantes sont utiles dans la production de xylitol et d'éthanol.

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