C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/13, 167/37,
C07K 14/725 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C12N 15/12 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01)
Patent
CA 1341042
The present invention provides purified polypeptides which comprise at least a portion of a .delta. T cell receptor polypeptide, a .gamma. T cell receptor polypeptide, a .gamma. , .delta. T cell receptor complex or a .gamma. , .delta. T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.
541220
Brenner Michael B.
Ip Stephen H.
Krangel Michael S.
Seidman Jonathan
Strominger Jack L.
Dana-Farber Cancer Institute Inc.
Gowling Lafleur Henderson Llp
President & Fellows Of Harvard College
T. Cell Sciences Inc.
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