C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) A61K 38/17 (2006.01)
Patent
CA 2623088
Y4 receptor agonist peptide selected from the group consisting of: [Ala30]PP2- 36, [Thr30]PP2-36 Asn30]PP2-36, [Gln30]PP2-36, [Glu10]PP2-36, [Glu10, Leu17,Thr3O]PP2-36, [Nle17,Nle3O]PP2-36, [Glu10,Nle17,Nle3O]PP2-36, their PPl- 36 equivalents, and analogues and derivatives thereof as described in the specification, are selective agonists of the Y4 receptor relative to the Y1 and Y2 receptors, and are useful in the treatment, for example, of obesity and overweight, and conditions in which these are considered contributory factors, and in the treatment of diarrhoea and intestinal hypersecretion.
Un peptide agoniste du récepteur Y4 sélectionné dans le groupe constitué par: [Ala30]PP2-36, [Thr30]PP2-36 Asn30]PP2-36, [Gln30]PP2-36, [Glu10]PP2-36, [Glu10, Leu17,Thr3O]PP2-36, [Nle17,Nle3O]PP2-36, [Glu10,Nle17,Nle3O]PP2-36, leurs équivalents PPl-36, analogues et dérivés tels que définis dans la description, sont des agonistes sélectifs du récepteur Y4, associé aux récepteurs Y1 et Y2, et sont utilisés dans le traitement, par exemple, de l'obésité et de la surcharge pondérale, d'états pathologiques dans lesquels ces agonistes sont considérés comme facteurs favorables, ainsi que dans le traitement de la diarrhée et de l'hypersécrétion intestinale.
Elling Christian
Gerlach Lars-Ole
Little Paul Brian
Schwartz Thue
7tm Pharma A/s
Gowling Lafleur Henderson Llp
LandOfFree
Y4 selective receptor agonists for therapeutic interventions does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Y4 selective receptor agonists for therapeutic interventions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Y4 selective receptor agonists for therapeutic interventions will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1888359