Yeast-based process for production of l-pac

Details Yeast-based process for production of l-pac Yeast-based process for production of l-pac

C - Chemistry, Metallurgy

12

P

C12P 7/26 (2006.01) C07C 45/45 (2006.01) C07C 49/245 (2006.01) C12P 7/28 (2006.01)

Patent

CA 2394265

The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supercritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is phenylacetylcarbinol, according to the reaction (I): in which the benzaldehyde, the pyruvic acid, or both may optionally be substituted.

L'invention concerne une méthode de synthèse d'un composé carbinol substitué ou non substitué, consistant à soumettre l'aldéhyde aromatique substitué ou non substitué correspondant à une condensation d'acyloïne activée par la levure, en présence soit (a) d'un fluide supercritique, (b) soit d'un gaz liquéfié, et à récupérer le composé carbinol. La levure est de préférence Saccharomyces cerevisiae. Dans un mode de réalisation préféré, l'aldéhyde aromatique est du benzaldéhyde et le carbinol du phénylacétylcarbinol, d'après la réaction (I) : dans laquelle le benzaldéhyde et/ou l'acide pyruvique peuvent être éventuellement substitués.

Affiliated with

Also associated with

Rating

Yeast-based process for production of l-pac does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Yeast-based process for production of l-pac, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Yeast-based process for production of l-pac will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1374310