Yeast-based vaccine for inducing an immune response

Details Yeast-based vaccine for inducing an immune response Yeast-based vaccine for inducing an immune response

A - Human Necessities

61

K

A61K 39/02 (2006.01)

Patent

CA 2638815

The invention provided herein relates to vaccines that can be tailored to achieve a desired immune response. Some compositions provided herein are used for preferentially eliciting a humoral immune response while other compositions are useful for preferentially eliciting a cell-mediated response. Combinations of vaccine compositions are also useful for eliciting both types of responses and/or for modulating the type of immune response elicited. The invention also provides methods for eliciting an immune response in an individual by administering the compositions disclosed herein. These immune responses are useful for protecting an individual from various types of diseases, infections, and undesirable conditions.

L'invention concerne des vaccins pouvant être spécialement formulés pour obtenir une réponse immunitaire voulue. De préférences, certaines compositions de l'invention sont utilisées pour déclencher une réponse immunitaire humorale, tandis que d'autres compositions sont utiles pour déclencher de préférence une réponse médiée par des cellules. L'invention concerne des combinaisons de compositions de vaccins utiles pour déclencher ces deux types de réponse et/ou pour moduler le type de réponse immunitaire déclenchée. L'invention concerne également des procédés destinés à déclencher une réponse immunitaire chez un individu par administration des compositions de l'invention à cet individu. Les réponses immunitaires sont utiles pour protéger un individu de types variés de maladies, d'infections et d'états pathologiques indésirables.

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