Yeast-based vaccines as immunotherapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61P 35/00 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2508957

Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.

Cette invention concerne des compositions et des méthodes permettant de traiter et/ou de prévenir diverses maladies et états pouvant faire l'objet d'une immunothérapie et, dans un mode de réalisation particulier, des compositions et des procédés de traitement et/ou de prévention du cancer chez l'animal. Spécifiquement, l'invention concerne des améliorations liées à l'utilisation d'un vaccin à base de levure comprenant un véhicule pour levure et un antigène choisi pour déclencher une réponse immunitaire cellulaire ou humorale spécifique de l'antigène chez l'animal, vaccin utilisé pour la vaccination thérapeutique et la prévention et/ou le traitement de diverses maladies et états pathologiques.

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