Yeast expression systems with vectors having gapdh or pyk...

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.3

C12N 15/81 (2006.01) C07K 14/02 (2006.01) C12N 15/51 (2006.01) C12N 15/62 (2006.01)

Patent

CA 1341302

Yeast cells containing DNA plasmids having foreign DNA, wherein foreign DNA is expressed, are described. For example, DNA coding for hepatitis B and its virus surface antigen (HBsAg) is ligated to a yeast plasmid to yield a product that is used to transform yeast cells. the plasmids of this invention have either GAPDH or PyK promoters, and are capable of replicating in either a yeast cell or a bacterial cell.

439701

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