Yeast membrane protein expression system and its application...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/81 (2006.01) C07K 14/40 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/18 (2006.01)

Patent

CA 2458561

The invention relates to an in vitro cell based expression system for overexpressing heterologous pump proteins associated with drug resistance into the membrane of the host cell for drug screening applications.

L'invention concerne un système d'expression cellulaire in vitro servant à surexprimer des protéines de pompage hétérologue associé à la résistance aux médicaments dans la membrane de la cellule hôte, ce système étant mis en application dans le criblage de médicaments.

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