Yeast strains with interrupted atf2 gene and uses

Details Yeast strains with interrupted atf2 gene and uses Yeast strains with interrupted atf2 gene and uses

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 1/19 (2006.01) C12N 9/10 (2006.01) C12P 33/00 (2006.01)

Patent

CA 2285686

The invention concerns a modified yeast strain wherein the acetyl-CoA pregnenolone acetyl-transferase activity (APAT) is eliminated by alteration of the gene coding for said activity and which results in stabilisation of the 3 beta -hydroxysteroids.

L'invention a pour objet un souche de levure modifiée dans laquelle l'activité acétyl-CoA prégnénolone acétyl-transférase (APAT) est éliminée par altération du gène codant pour cette activité et dont il résulte une stabilisation des 3.beta.-hydroxystéroïdes.

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