Yeast with increased butanol tolerance involving a multidrug...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 1/16 (2006.01) C12N 1/18 (2006.01) C12P 7/16 (2006.01)

Patent

CA 2751529

Increasing tolerance to butanol in yeast has been accomplished by decreasing activity of Pdr5p encoded by an endogenous PDR5 gene. A deletion mutation of the PDR5 gene led to improved growth yield in the presence of butanol. Yeast cells with reduced Pdr5p activity, or other multidrug resistance ATP-binding cassette transporter protein activity encoded by CDR1 or BFR1, and a butanol biosynthetic pathway may be used for improved butanol production

Selon la présente invention, une tolérance augmentée au butanol chez la levure a été obtenue en diminuant l'activité de Pdr5p codée par un gène PDR5 endogène. Une mutation par délétion du gène PDR5 a conduit à un rendement de croissance amélioré en présence de butanol. Les cellules de levure avec une activité Pdr5p réduite, ou une autre activité de protéine de transporteur de cassette de liaison d'ATP de multirésistance aux médicaments codée par CDR1 ou BFR1, et une voie de biosynthèse de butanol peuvent être utilisées pour une production de butanol améliorée.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Yeast with increased butanol tolerance involving a multidrug... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Yeast with increased butanol tolerance involving a multidrug..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Yeast with increased butanol tolerance involving a multidrug... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1947486

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.