Zace1: a human metalloenzyme

Details Zace1: a human metalloenzyme Zace1: a human metalloenzyme

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C07K 16/40 (2006.01) C07K 16/42 (2006.01) C07K 19/00 (2006.01) C12N 9/64 (2006.01) C12N 15/63 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2352083

Angiotensin-converting enzyme is a zinc metallopeptidase that plays roles in blood pressure regulation and fertility. The catalytic activities of angiotensin converting enzymes include the production of the potent vasopressor angiotensin II from angiotensin I, and the inactivation of the vasodilatory peptide bradykinin. Zace1 is a form of human zinc metallopeptidas, which includes one zinc-dependent catalytic domain containing the motif "HEXXH" and one downstream "EX(I/V)X(D/S)" motif.

L'invention a trait à une enzyme de conversion de l'angiotensine qui est une métallopeptidase à zinc jouant un rôle dans la régulation de la pression artérielle et la fécondité. Parmi les activités catalysantes des enzymes de conversion de l'angiotensine figurent la production, à partir de l'angiotensine I, d'angiotensine II, qui est un puissant vasopresseur, et l'inactivation de la bradykinine, qui est un peptide vasodilatateur. Zace1 est une forme de métallopeptidases à zinc humaines, qui comprennent un domaine catalytique dépendant du zinc contenant le motif <= HEXXH >= ainsi qu'un motif <= EX(I/V)X(D/S) >= en aval.

Affiliated with

Also associated with

Rating

Zace1: a human metalloenzyme does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Zace1: a human metalloenzyme, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Zace1: a human metalloenzyme will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2056298