Zcytor7 cytokine receptor

Details Zcytor7 cytokine receptor Zcytor7 cytokine receptor

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C07K 16/42 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2281491

Novel cytokine receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular domain of a cell-surface receptor that is expressed in kidneys, pancreas, prostate, adrenal cortex and nervous tissue. The polypeptides may be used within methods for detecting ligands that promote the proliferation and/or differentiation of these organs.

Cette invention se rapporte à de nouveaux polypeptides récepteurs de cytokine, à des polynucléotides codant ces polypeptides, et à des compositions et procédés associés. Lesdits polypeptides comportent un domaine extracellulaire d'un récepteur de surface cellulaire qui est exprimé dans les reins, le pancréas, la prostate, le cortex surrénal et le tissu nerveux. Ces polypeptides peuvent être utilisés dans des procédés de détection de ligands qui favorisent la prolifération et/ou la différentiation de ces organes.

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