Zinc finger binding domains for gnn

C - Chemistry – Metallurgy – 12 – N

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C12N 15/10 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2347025

Zinc finger-nucleotide binding polypeptides having binding specificity for target nucleotides containing one or GNN triplets are provided. Compositions containing such polypeptides and the use of such polypeptides and compositions for regulating nucleotide function are also provided.

L'invention porte sur des polypeptides de liaison des doigts de zinc ayant une spécificité de liaison pour des nucléotides cibles contenant un ou des triplets de GNN. L'invention porte également sur des compositions contenant ces polypeptides et sur l'utilisation de ces polypeptides et de ces compositions pour réguler la fonction nucléotidique.

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